Following are a half-century of OSBA region secretaries, their years of service and their professional affiliations.
| Central Region | ||
| 1956 | K.C. DeGood and John Corbally | The Ohio State University |
| 1957 | John Corbally | The Ohio State University |
| 1958 | John Corbally and William Frederick Staub | The Ohio State University |
| 1959-1962 | William Frederick Staub | The Ohio State University |
| 1963 | William Frederick Staub and Roy Larmee | The Ohio State University |
| 1964 | Edward Yarnell | The Ohio State University |
| 1965-1966 | Virgil Blanke | The Ohio State University |
| 1967-1968 | Dr. Lewis E. Harris, temporary secretary | OSBA executive director |
| 1967-1971 | John Simon | OSBA assistant director |
| 1972-1984 | Craig Gifford | 1972–1980 OSBA deputy executive vice president; 1981–1984 OSBA executive director |
| 1984-1998 | Timothy G. Kremer | 1984–1993 OSBA director of communication and information services; 1994–1998 OSBA deputy executive director |
| 1998-1999 | John M. Brandt | OSBA executive director |
| 1999-2005 | Dr. Sherry Lahr | Ashland University |
| 2006-2013 | Dr. Michael G. Grote | former Delaware City board member, 2004 OSBA president |
| 2014-2022 | Kim Miller-Smith | former Canal Winchester Local (Franklin) superintendent |
| Northeast Region | ||
| 1956-1961 | Dr. Roger Shaw | Kent State University |
| 1962 | Dr. Roger Shaw and Paul K. Howells |
Kent State University |
| 1963 | Paul K. Howells | Kent State University |
| 1964 | Roger Beitler | Kent State University |
| 1964-1974 | Glenn Maynard | Kent State University |
| 1975-1976 | Harold Van Winkle | Kent State University |
| 1977 | Harold Van Winkle and Dr. Harold R. Walker |
Kent State University and Malone College, respectively |
| 1978-1996 | Dr. Harold R. Walker | Malone College |
| 1996-2001 | Dr. Jay Parrot | Canton City Schools administrator |
| 2001-2010 | Russell B. McKenzie | former Southeast Local (Portage) board member |
| 2011-2014 | Terri Neff | former Brecksville-Broadview Heights City board member |
| 2014-present | Reno Contipelli | former Cuyahoga Heights Local (Cuyahoga) board member |
| Northwest Region | ||
| 1956-1961 | Dr. John Gee | Bowling Green State University |
| 1962 | Dr. John Gee and Ralph H. Geer |
Bowling Green State University |
| 1963-1971 | Ralph H. Geer | Bowling Green State University |
| 1972 | Ralph H. Geer and Dr. Neil Pohlmann |
Bowling Green State University |
| 1973 | Ralph H. Geer | Bowling Green State University |
| 1974-1996 | Dr. Neil Pohlmann | Bowling Green State University |
| 1997-2000 | Dr. Eugene Sanders | Bowling Green State University |
| 2001-2002 | Dr. David A. Nicholls | Bowling Green State University |
| 2002–2021 | Dr. Judy Jackson May | Bowling Green State University |
| Southeast Region | ||
| 1956 | Dr. F.H. McKelvey | Ohio University |
| 1957-1959 | Gilford Crowell | Ohio University |
| 1960 | Gilford Crowell and Russell Milliken |
Ohio University |
| 1961-1963 | Russell Milliken | Ohio University |
| 1964-1965 | O. Paul Roaden | Ohio University |
| 1966-1970 | Russell Milliken | Ohio University |
| 1971-1972 | Gilford Crowell | Ohio University |
| 1973-1987 | Harry Lackey | Ohio University |
| 1987-1993 | Dr. Paul Dressell | Ohio University |
| 1994-1998 | Don Cain | former Zanesville City board member, 1986 OSBA president |
| 1999–present | Paul D. Mock | former Logan-Hocking Local (Hocking) board member, 1997 OSBA president |
| Southwest Region | ||
| 1956-1973 | Dr. H.I. Von Haden | Miami University |
| 1974 | Craig Gifford | OSBA deputy executive vice president |
| 1974-2000 | Dr. Albert W. Kettlewell | Miami University |
| 2000-2020 | Ron Diver | former Carlisle Local (Warren) board member, 1998 OSBA President |
| 2020-present | Mark Ewing | former Batavia Local (Clermont) board member |